Correctly recognize the causes of the emergence of depression

核心提示: 大样本人群遗传流行病学调查显示，与患病者血缘关系愈近，患病概率越高。 The probability of first-degree relatives having the disease is much higher than that of other relatives, which is consistent with the general pattern of genetic diseases .

　　Many people think that depression is only found in introverted and unsocialized people, but it's actually more than that. With the changes in the environment and psychological changes that people are in, the emergence of depression is also diverse, so you need to objectively understand the causes of the emergence of depression so that you can better recognize it. No matter how complex the causes of depression are, as long as you keep your inner balance you will not suffer from such diseases.

　　 (1) Genetic factors: a large sample of the population genetic epidemiological survey shows that the closer the blood relationship with the patient, the higher the probability of illness. The probability of first-degree relatives suffering from the disease is much higher than that of other relatives, which is consistent with the general pattern of genetic diseases.

　　 (2) Biochemical factors: catecholamine hypothesis: mainly refers to the occurrence of depression may be related to the brain synaptic gap neurotransmitter 5-hydroxytryptamine (5-HT) and norepinephrine (NE) concentration decline; due to the use of many antidepressants, such as selective 5-hydroxytryptamine reuptake inhibitors (SSRI) or selective 5-hydroxytryptamine and norepinephrine reuptake inhibitors (SNRI) and so on. Although the concentration of these neurotransmitters in the synaptic gap of the brain rises quickly, the antidepressant effect generally takes about 2 weeks to take effect, thus the hypothesis of increased sensitivity of 5-HT and NE receptors (hypersensitivity); and

　　 (3) Psycho-social factors: the sudden onset of various major life events, or their long-term persistence can cause intense or (and) persistent unpleasant emotional experiences, leading to depression.

　　The emergence of depression is not caused by a single reason, so when dealing with depression patients also need to be treated from various aspects. Although depression has a genetic component to it, there is no need to worry too much about it, as depression is also a modifiable condition that will not have serious consequences if it is well regulated.