What are the causes of depression?

　　Depression is a relatively stubborn mental illness that often occurs in our lives, and it has a strong recurrence. Patients suffering from depression suffer from mental pain for a long time. In order to help the majority of friends understand depression, the following is a list of several common causes of depression.

　　(1) genetic factors: a large sample of the population genetic epidemiological survey shows that the closer the blood relationship with the patient, the higher the probability of illness. The probability of first-degree relatives suffering from the disease is much higher than that of other relatives, which is consistent with the general law of genetic diseases.

　　(2) Biochemical factors: catecholamine hypothesis: mainly refers to the occurrence of depression may be related to the brain synaptic gap neurotransmitter 5-hydroxytryptamine (5-HT) and norepinephrine (NE) concentration decline; due to the use of many antidepressants, such as selective 5-hydroxytryptamine reuptake inhibitors (SSRI) or selective 5-hydroxytryptamine and norepinephrine reuptake inhibitors (SNRI) and so on. Although the concentration of these neurotransmitters in the synaptic gap of the brain rises quickly, the antidepressant effect generally takes about 2 weeks to take effect, thus the hypothesis of increased sensitivity of 5-HT and NE receptors (hypersensitivity); and

　　(3) Psycho-social factors: the sudden occurrence of various major life events, or the long-term persistence will cause strong or (and) lasting unpleasant emotional experience, leading to depression.

　　Depression is a mental illness that can be found everywhere in our lives, and it seriously affects the physical health and physical health of the patient, causing a devastating impact on our lives. If you are a patient with depression, the above mentioned causes are for reference only, please consult a specialist in psychiatry for specific details.