What are the causes of depression?

　　Nowadays, the pace of life in society is getting faster and faster, and the pressure of competition is increasing, which leads to an increasing incidence of depression. I wonder if you have ever considered how depression occurs? Many people will think that it is caused by too much pressure, however, high pressure is not the only cause of depression, let's look at the following detailed description of the causes of depression.

　　 1.Neuroendocrine dysfunction:

　　Many studies have found that patients with depression have abnormal function of the hypothalamus a pituitary an adrenal axis, and that patients with depression have increased levels of plasma corticosteroid and 17-hydroxycorticosteroids. Normal people taking dexamethasone, can inhibit cortisol secretion, and depressed patients taking dexamethasone, did not see the phenomenon of inhibition of cortisol should be, this is used to diagnose depression of the so-called "dexamethasone suppression test" (DST), not only to help diagnose depression, but also can be identified as an affective psychosis depression, or depression Depression is not only helpful in diagnosing depression, but also in identifying whether it is an affective psychotic depression or a depressive disorder.

　　 2.Biochemical Metabolism:

　　Neurotransmitters in the brain are one of the more researched elements, and this theoretical hypothesis is mainly derived from psychopharmacological studies. Clinical studies have found that the amount of urinary norepinephrine metabolites is significantly lower in certain depressed patients than in controls, reflecting a decrease in norepinephrine in the patient's brain, and, interestingly, this metabolite is discharged higher in the urine when the depression turns into mania, suggesting that mania and depression are related to the amount of norepinephrine in the brain. It has also been found that both manic and depressed patients have low levels of individual serotonin and its metabolites in the brain, cerebrospinal fluid, and urine.

　 　3.Genetic factors:

　　Many studies have found a closer relationship between the occurrence of depression and genetic factors, but depression is not a hereditary disease, and genetic studies have been conducted mainly through investigations of family trees and studies of twins. Genetic factors have a definite role in the development of depression, but this mainly refers to affective psychotic depression. As for other mild depressive disorders such as depressive neurosis and reactive depression personality and environmental factors may play a greater role.

　　 4.Psychological and social factors:

　　More than half of the first onset of depression patients can be found to have psychological and social factors, but there is a lot to say, depressive neurosis and reactive depression onset of psychological and social factors exist without exception, especially the latter is obvious, there is no mental stimulation how to reactive depression? But as for affective psychosis of depression whether the onset of mental stimulation, or worthy of careful scrutiny, some patients actually exist first depressed mood, on the basis of which encountered some of the general population is not a stimulus to the "mental stimulation".

　　The above is about the four common causes of depression, it can be seen that the causes of depression is more complex, but the majority of patients with the onset of psychological factors, so the patient in the active use of medication at the same time also need to cooperate with the doctor's psychotherapy, and always maintain a positive and optimistic attitude, so that we can soon recover health.