What can be the factors that contribute to the onset of depression

　　Depression will plague the patient's usual life, at the same time will harm the physical and mental health of the patient's friends, we need to trigger the emergence of depression to pay attention to the factors can only be, only they can facilitate everyone to cope with depression, then in the end what kind of reasons triggered the emergence of depression, next to recognize it.

　　 The causes of depression:

　　1.Neuroendocrine dysfunction: many studies have found that patients with depression have abnormal hypothalamus-pituitary-adrenal axis function, and patients with depression have increased plasma corticosteroid and 17-hydroxycorticosteroid levels. Normal people taking dexamethasone, can inhibit the secretion of cortisol, and depressed patients taking dexamethasone, did not see the inhibition of cortisol should be phenomenon, this is used to diagnose depression, the so-called dexamethasone suppression test (dst), not only can help to diagnose depression, but also can be identified as affective psychosis depression, or depressive neurosis.

　　2.Biochemical metabolism: neurotransmitters in the brain is one of the more researched elements, this theoretical hypothesis is mainly derived from psychopharmacological research. Clinical studies have found that the amount of norepinephrine metabolites in the urine of certain depressed patients is significantly lower than that of the control group, reflecting a decrease in norepinephrine in the brain of the patient, and it is interesting to note that this metabolite is discharged higher in the urine when the depression turns into mania, which suggests that mania and depression are related to the amount of norepinephrine in the brain. Another study found that both manic and depressed patients have low levels of norepinephrine and its metabolites in the brain, cerebrospinal fluid, and urine.

　　3.Genetic factors: many studies have found that the occurrence of depression and genetic factors have a closer relationship, but depression is not a hereditary disease, genetic research is mainly through the investigation of genealogy and the study of twins. Genetic factors have a definite role in the development of depression, but this mainly refers to affective psychotic depression. For other mild forms of depression, such as depressive neurosis and reactive depression, personality and environmental factors may play a greater role.

　　4.Psychological and social factors: more than half of the first onset of depression patients can be found to have psychological and social factors, but there is a lot to say, depressive neurosis and reactive depression, without exception, there are psychological and social factors, especially the latter is obvious, there is no mental stimulation how to reactive depression? But as for affective psychosis of depression is related to mental stimulation, or worthy of careful scrutiny, some patients actually exist in the first depressed mood, on the basis of which encountered some of the general people do not stimulate the mental stimulation. Causes of depression have the above four types of etiology, most of the patients with psychological factors related to the treatment of depression in addition to psychotherapy and drug therapy, but also with a reasonable combination of psychiatrist's counseling, can be effective in alleviating the condition.

　　 Symptoms of depression:

　　1, depressed state of mind: the physical symptoms of depression are low mood, distress and sadness, and lack of interest. Feel pessimistic and despairing, painful and unbearable, with the feeling that days are like years and life is worse than death. Commonly used to live meaningless, not happy to describe their inner experience. Typical people have a depressed mood, characterized by heavy daytime and light nighttime. It often coexists with anxiety. Decreased volitional activity, a marked reduction in active activities, passive life, unwilling to participate in the outside world and activities of interest, often alone. The patient's life is characterized by laziness, which develops into speechlessness and immobility, up to the point of rigidity. The most dangerous thing is the recurrence of suicide attempts and behavior.

　　2, slow thinking: thought association process is inhibited, slow reaction, self-conscious brain does not turn, manifested in the active speech reduction, speech slowed down significantly, thinking about the problem of laborious. Slow response, need to wait for a long time, under the influence of emotional depression, low self-evaluation, low self-esteem, a sense of uselessness and worthlessness, feel meaningless to live, pessimism and suicide intention, self-blame and self-incrimination, think that living has become a burden, committed a major crime, in the physical discomfort based on the emergence of the concept of hypochondriacs, think that he suffers from an incurable disease.

　　3, physical symptoms: most patients have physical symptoms of depression and other biological symptoms, such as palpitations, chest tightness, gastrointestinal discomfort, constipation, loss of appetite and weight loss. Sleep disorders are prominent, mostly difficulty in falling asleep. Elsewhere, hallucinations, depersonalization, dissolution of reality, obsessive-compulsive and phobic symptoms can also occur during depressive episodes. Because of the significant delay in thought association and memory loss, it is easy to affect the cognitive function of the elderly patients, and depressive pseudo-dementia occurs.

　　Through these introductions, we have learned what are the factors of depression, this is a more complex etiology of mental illness, after touching the patient's life, but also bring them serious harm, we should be triggered by the emergence of depression to understand the factors, in particular, to start the prevention of depression only.