What are the causes of depression?

　　The emergence of depression has been a long time, but, so far, it is not clear what is the specific cause of the onset of this disease, what is caused by, but also need further research in the medical community, now the conclusion is that depression is the result of the interaction of a variety of factors.
　　 (1) Genetic factors: a large sample of population genetic epidemiological survey shows that the closer the blood relationship with the diseased person, the higher the probability of disease. The probability of first-degree relatives having the disease is much higher than that of other relatives, which is consistent with the general pattern of genetic diseases.
　　 (2) Biochemical factors: catecholamine hypothesis: mainly refers to the occurrence of depression may be related to the brain synaptic gap neurotransmitter 5-hydroxytryptamine (5-HT) and norepinephrine (NE) concentration decline; due to the use of many antidepressants, such as selective 5-hydroxytryptamine reuptake inhibitors (SSRI) or selective 5-hydroxytryptamine and norepinephrine reuptake inhibitors (SNRI) and so on. Although the concentration of these neurotransmitters in the synaptic gap of the brain rises quickly, the antidepressant effect usually takes about 2 weeks to take effect, so there is the hypothesis of increased sensitivity (hypersensitivity) of 5-HT and NE receptors;
(3) Psycho-social factors: the sudden occurrence of various major life events, or the persistence of a long period of time can cause intense or (and) persistent unpleasant emotional experience, leading to depression. The generation of depression.
　　Through the above simple introduction to depression, I believe we have a preliminary understanding, depression can actually be controlled and alleviated through a variety of methods, the patient should not be discouraged, as long as the active cooperation with the treatment, you will be able to see the results and alleviate the condition.