Causes of the onset of depression

　　With the development of society, people's living standards continue to improve, now everyone's work and life is more and more pressure, so a variety of mental illnesses continue to appear, which is a very common disease, the next we will introduce you to the causes of depression related content.

　　So far, the etiology and pathogenesis of depression is not clear, there are no obvious signs and laboratory indicators of abnormality, summarized as a result of the interaction of biological, psychological, social (cultural) factors. It is also because the cause of depression is unknown, there are many hypotheses about it, the more commonly recognized etiological assumptions include:

　　 (1) Genetic factors: a large sample of population genetic epidemiological survey shows that the closer the blood relationship with the patient, the higher the probability of disease. The probability of first-degree relatives having the disease is much higher than that of other relatives, which is consistent with the general pattern of genetic diseases.

　　 (2) Biochemical factors: catecholamine hypothesis: mainly refers to the occurrence of depression may be related to the brain synaptic gap neurotransmitter 5-hydroxytryptamine (5-ht) and norepinephrine (ne) concentration decline; due to the use of many antidepressants, such as selective 5-hydroxytryptamine reuptake inhibitor (ssri) or selective 5-hydroxytryptamine and norepinephrine reuptake inhibitor (snri) and so on Although the concentration of these neurotransmitters in the synaptic gap of the brain rises quickly, the antidepressant effect generally takes about 2 weeks to take effect, thus the hypothesis of increased sensitivity of 5-ht and ne receptors (hypersensitivity); and

　　 (3) psycho-social factors: a variety of major life events occur suddenly, or long-term persistence will cause strong or (and) lasting unpleasant emotional experience, resulting in depression.

　　The above is the entire content of this article, this article through a detailed, specific introduction to the causes of depression common sense knowledge, I hope to help patients with such problems as well as patients' families. I hope that the patients can actively accept the treatment, early recovery of health. At the same time, each of us should also develop a reasonable and healthy habits, to maintain good health.