Introducing Physical Causes of Depression

　　Depression this disease brings a lot of trouble, but also affects the patient's daily life, friends should pay attention to the disease of depression, the need to correctly understand some of the factors that triggered the emergence of depression to facilitate the patients and friends of the depression to cope with, to understand the causes of the emergence of depression will have what it is.

　　 The causes of depression:

　　1.Neuroendocrine dysfunction: many studies have found that depressed patients have hypothalamus a pituitary an adrenal axis function abnormality, plasma corticosteroid and 17-hydroxycorticosteroid content is increased in depressed patients. Normal people taking dexamethasone, can inhibit the secretion of cortisol, and depressed patients taking dexamethasone, did not see the inhibition of the phenomenon of cortisol should be, this is used to diagnose depression, the so-called "dexamethasone suppression test" (dst), not only to help diagnosis of depression, but also can be identified as an affective psychosis depression, or depressive neurosis.

　　2.Biochemical metabolism: neurotransmitters in the brain is one of the more researched content, this theoretical hypothesis mainly from the psychopharmacology research. Clinical studies have found that the amount of norepinephrine metabolites in the urine of certain depressed patients is significantly lower than that of the control group, reflecting a decrease in norepinephrine in the patient's brain, and it is interesting to note that this metabolite is discharged higher in the urine when the depression turns into mania, which suggests that mania and depression are related to the amount of norepinephrine in the brain. It has also been found that cerebral, cerebrospinal fluid and urinary levels of norepinephrine and its metabolites are low in both manic and depressed patients.

　　3.Genetic factors: many studies have found that the occurrence of depression and genetic factors have a closer relationship, but depression is not a hereditary disease, genetic research is mainly through the investigation of genealogy and the study of twins. Genetic factors have a definite role in the development of depression, but this mainly refers to affective psychotic depression. For other mild forms of depression, such as depressive neurosis and reactive depression, personality and environmental factors may play a greater role.

　　4.Psychological and social factors: more than half of the first onset of depression patients can be found to have psychological and social factors, but there is a lot to say, depressive neurosis and reactive depression, without exception, there are psychological and social factors, especially the latter is obvious, there is no mental stimulation how to reactive depression? But as for affective psychosis of depression is related to mental stimulation, or worthy of detailed speculation, some patients actually exist in the first depressed mood, on the basis of which encountered some of the general people do not stimulate the "mental stimulation".

　　5.Endocrine dysfunction is a common cause of depression: many studies have found that patients with depression have abnormal function of hypothalamus-pituitary-adrenal axis, and plasma corticosteroid and 17-hydroxycorticosteroid levels are increased in patients with depression. Physical disease, some serious physical diseases, such as stroke, heart attack, hormone disorders often trigger depression, and make the original disease worse. In addition, 1/3 of people with depression have substance abuse problems. Psychological and social factors is one of the important causes of the increase in the number of patients with depression, the first onset of depression, more than half of the patients can be found to have psychological and social factors, but there is a lot to say, depressive neurosis and reactive depression, the onset of the psychological and social factors exist without exception, especially the latter is obvious, there is no mental stimulation how to reactive depression it?

　　Factors leading to the emergence of depression is the above knowledge, depression is particularly terrible, and bring very much harm to the patient, we need to know more about some of the knowledge of the disease of depression, need to analyze the causes of the above, in the life of the onset of depression to avoid the factors to be able to.