Causes of depression

　　In modern life, with the continuous development and progress of social and economic development and the continuous improvement of people's living standards, each of us faces more and more pressure from learning, work, life, we can easily form an unhealthy, irrational, irregular dietary habits. This leads to the occurrence of various diseases. Depression is a relatively common disease in recent years. This article will introduce the causes of depression.

　　So far, the etiology and pathogenesis of depression is not clear, there are no obvious signs and laboratory indicators of abnormality, summarized as a result of the interaction of biological, psychological and social (cultural) factors. It is also because the cause of depression is unknown, there are many hypotheses about it, the more commonly recognized etiological assumptions include:

　　(1) Genetic factors: a large sample of population genetic epidemiological survey shows that the closer the blood relationship with the patient, the higher the probability of disease. The probability of first-degree relatives having the disease is much higher than that of other relatives, which is consistent with the general pattern of genetic diseases.

　　(2) Biochemical factors: catecholamine hypothesis: mainly refers to the occurrence of depression may be related to the brain synaptic gap neurotransmitter 5-hydroxytryptamine (5-ht) and norepinephrine (ne) concentration decline; due to the use of many antidepressants, such as selective 5-hydroxytryptamine reuptake inhibitor (ssri) or selective 5-hydroxytryptamine and norepinephrine reuptake inhibitor (snri) and so on Although the concentration of these neurotransmitters in the synaptic gap of the brain rises quickly, the antidepressant effect generally takes about 2 weeks to take effect, thus the hypothesis of increased sensitivity of 5-ht and ne receptors (hypersensitivity); and

　　(3) psycho-social factors: a variety of major life events occur suddenly, or long-term persistence will cause strong or (and) lasting unpleasant emotional experience, leading to depression.

　　Through the reading of the article above I think we must know, what is the cause of depression, I hope that these contents can bring help to everyone, at the same time to remind everyone, life actively do prevention, maintain an optimistic state of mind is very important, if found to suffer from the disease, then we must timely examination and treatment, so as to be able to avoid the harm caused by depression.